Quantification of radiotracer uptake with a dedicated breast PET imaging system
نویسندگان
چکیده
منابع مشابه
Molecular Imaging in Breast Cancer: From Whole-Body PET/CT to Dedicated Breast PET
Positron emission tomography (PET), with or without integrated computed tomography (CT), using 18F-fluorodeoxyglucose (FDG) is based on the principle of elevated glucose metabolism in malignant tumors, and its use in breast cancer patients is frequently being investigated. It has been shown useful for classification, staging, and response monitoring, both in primary and recurrent disease. Howev...
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Galectin-3 (Gal-3) is a β-galactosidase binding protein that modulates various cellular processes including cell adhesion, and metastasis. We evaluated the tumor targeting and imaging properties of a galectin-3 binding peptide originally selected from bacteriophage display, in a mouse model of human breast carcinoma expressing galectin-3. A galectin-3 binding peptide, ANTPCGPYTHDCPVKR, was synt...
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Two methodologies for fitting radiotracer models on a pixel-wise basis to PET data are considered. The first method does parameter optimization for each pixel considered as a separate region of interest. The second method also does pixel-wise analysis but incorporates an additive mixture representation to account for heterogeneity effects induced by instrumental and biological blurring. Several...
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ژورنال
عنوان ژورنال: Medical Physics
سال: 2008
ISSN: 0094-2405,2473-4209
DOI: 10.1118/1.2990781